Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420722 | 1.00 | PBRM1 (0.49) | PBRM1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11414913 | 0.88 | PBRM1 (0.62) | PBRM1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11414915 | 0.88 | PBRM1 (0.62) | PBRM1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11404092 | 0.83 | ALDH1A1 (0.54) | PBRM1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11404090 | 0.83 | ALDH1A1 (0.54) | PBRM1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11405806 | 0.82 | PTGS2 (0.49) | PBRM1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11405802 | 0.82 | PTGS2 (0.49) | PBRM1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11408187 | 0.81 | PTGS2 (0.50) | PBRM1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11408184 | 0.81 | PTGS2 (0.50) | PBRM1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL11408177 | 0.79 | KDM4E (0.53) | PBRM1KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230727-A | N-BENZYLIDENEANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4187317-A | Sunscreen and erythema treating with N-benzylidene anilenes | WILLIAM H. RORER, INC. (US) | 1980-02-05 | — | — | US | disclosed |