Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23531290 | 0.87 | — | — | |
| SCHEMBL23531309 | 0.83 | — | — | |
| SCHEMBL23531388 | 0.79 | MAPT (0.34) | — | |
| SCHEMBL2664318 | 0.74 | ALDH1A1 (0.34) | POLB | |
| SCHEMBL496821 | 0.68 | CYP1A2 (0.35) | — | |
| SCHEMBL18415072 | 0.68 | CYP2C19 (0.43) | — | |
| SCHEMBL2664317 | 0.67 | RAB9A (0.32) | POLB | |
| SCHEMBL399747 | 0.67 | — | — | |
| SCHEMBL21047594 | 0.67 | — | — | |
| SCHEMBL25699393 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218566-A | BRONCHODILATORS, ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| US-4189597-A | PROSTAGLANDINS, BRONCHODILATORS | AMERICAN CYANAMID COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4165331-A | PROSTAGLANDINS/AND DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4154959-A | 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154954-A | BRONCHODILATOR AGENTS; ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4085272-A | BRONCHODILATORS, INFLAMMATORY MEDEATOR RELEASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-04-18 | — | — | US | disclosed |