Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CD40 | P25942 | 1/20 | 0.46 |
| ▸ | CD40LG | P29965 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439150 | 0.92 | MAPT (0.52) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11424949 | 0.92 | HPGD (0.59) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11426564 | 0.89 | HPGD (0.55) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11433945 | 0.89 | HPGD (0.55) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11431850 | 0.88 | HPGD (0.62) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11423955 | 0.88 | HPGD (0.52) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11430244 | 0.85 | MAPT (0.53) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11424306 | 0.84 | MAPT (0.57) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11422144 | 0.84 | KCNMA1 (0.48) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL11437898 | 0.84 | HPGD (0.59) | MAPTLMNAHTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |