Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439150 | 0.96 | MAPT (0.52) | HPGDMAPTLMNAHTTALDH1A1 | |
| SCHEMBL11426564 | 0.93 | HPGD (0.55) | HPGDMAPTLMNAHTTALDH1A1 | |
| SCHEMBL11426047 | 0.92 | HPGD (0.62) | HPGDMAPTLMNAHTTALDH1A1 | |
| SCHEMBL11433945 | 0.89 | HPGD (0.55) | HPGDMAPTLMNAHTTALDH1A1 | |
| SCHEMBL11437898 | 0.88 | HPGD (0.59) | HPGDMAPTLMNAHTTALDH1A1 | |
| SCHEMBL11422142 | 0.88 | MAPT (0.52) | HPGDMAPTLMNAHTTALDH1A1 | |
| SCHEMBL11424280 | 0.85 | MAPT (0.51) | HPGDMAPTLMNAHTTALDH1A1 | |
| SCHEMBL11437122 | 0.85 | HPGD (0.66) | HPGDMAPTLMNAHTTALDH1A1 | |
| SCHEMBL10905389 | 0.85 | TIMP3 (0.50) | HPGDMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL11341781 | 0.85 | HPSE (0.55) | HPGDMAPTLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |