Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.44 |
| ▸ | DNA2 | P51530 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422864 | 0.83 | CDK2 (0.52) | CDK2TSHRSLC25A1DNA2CASP6 | |
| SCHEMBL4442634 | 0.80 | TSHR (0.56) | CDK2TSHRDNA2CASP6CTDSP1 | |
| SCHEMBL31401808 | 0.80 | TSHR (0.56) | CDK2TSHRDNA2CASP6CTDSP1 | |
| SCHEMBL11435699 | 0.79 | CDK2 (0.52) | CDK2TSHRSLC25A1DNA2CASP6 | |
| SCHEMBL9279173 | 0.78 | CDK2 (0.52) | CDK2TSHRDNA2CASP6CTDSP1 | |
| SCHEMBL309038 | 0.76 | TSHR (0.64) | TSHRSLC25A1DNA2CASP6CTDSP1 | |
| SCHEMBL11429697 | 0.75 | DTYMK (0.45) | CDK2TSHRSLC25A1CASP6DTYMK | |
| SCHEMBL27827942 | 0.74 | TSHR (0.62) | TSHRSLC25A1DNA2CASP6CTDSP1 | |
| SCHEMBL12603011 | 0.74 | GPR35 (0.53) | TSHRSLC25A1CASP6DTYMKGPR35 | |
| SCHEMBL28638357 | 0.73 | CDK2 (0.56) | CDK2TSHRDNA2CASP6CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4212813-A | OXIDIZING ACENAPHTHENES, COBALT COMPOUND CATALYST | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-07-15 | — | — | US | disclosed |