Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575661 | 0.84 | ALDH1A1 (0.61) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL29484175 | 0.81 | ALDH1A1 (0.71) | ALDH1A1PKMKMT2AMEN1TDP1 | |
| SCHEMBL3822991 | 0.80 | ALDH1A1 (1.00) | ALDH1A1PKMKMT2AMEN1TDP1 | |
| SCHEMBL6211890 | 0.77 | ALDH1A1 (0.80) | ALDH1A1PKMKMT2AMEN1TDP1 | |
| SCHEMBL4588187 | 0.77 | ALDH1A1 (0.62) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL318068 | 0.77 | ALDH1A1 (0.73) | ALDH1A1PKMKMT2AMEN1TDP1 | |
| SCHEMBL16562180 | 0.77 | ALDH1A1 (0.69) | ALDH1A1PKMKMT2AMEN1NPC1 | |
| SCHEMBL18894145 | 0.77 | ALDH1A1 (0.73) | ALDH1A1PKMADAMTS5KMT2AMEN1 | |
| SCHEMBL9177530 | 0.76 | ALDH1A1 (0.71) | ALDH1A1PKMKMT2AMEN1TDP1 | |
| SCHEMBL20496927 | 0.76 | ALDH1A1 (0.83) | ALDH1A1PKMKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183925-A | 7-Aminophenylacetamido-Δ3 -cephem antibacterial agents and method of use | PFIZER INC. (US) | 1980-01-15 | — | — | US | disclosed |
| US-4144240-A | USED FOR MODIFYING CEPHALOSPORINS | PFIZER INC. (US) | 1979-03-13 | — | — | US | disclosed |