Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422945 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10TSHRKDM4E | |
| SCHEMBL11428163 | 0.91 | KDM4E (0.45) | ALDH1A1HPGDHSD17B10KDM4EABL1 | |
| SCHEMBL11428164 | 0.91 | KDM4E (0.45) | ALDH1A1HPGDHSD17B10KDM4EABL1 | |
| SCHEMBL11408874 | 0.84 | MEN1 (0.45) | ALDH1A1HPGDHSD17B10TSHRKDM4E | |
| SCHEMBL11408875 | 0.84 | MEN1 (0.45) | ALDH1A1HPGDHSD17B10TSHRKDM4E | |
| SCHEMBL11408879 | 0.80 | CA1 (0.46) | ALDH1A1HPGDHSD17B10KDM4EABL1 | |
| SCHEMBL11423214 | 0.80 | CA1 (0.46) | ALDH1A1HPGDHSD17B10KDM4EABL1 | |
| SCHEMBL11418993 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10TSHRKDM4E | |
| SCHEMBL11418991 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10TSHRKDM4E | |
| SCHEMBL11431151 | 0.75 | MEN1 (0.46) | ALDH1A1HPGDHSD17B10TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |