Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | CDH1 | P12830 | 1/20 | 0.37 |
| ▸ | APC | P25054 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408875 | 1.00 | MEN1 (0.45) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL11431148 | 0.88 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL11431151 | 0.88 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL11409738 | 0.87 | LMNA (0.48) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL11409741 | 0.87 | LMNA (0.48) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL11422940 | 0.84 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL11422945 | 0.84 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL11410085 | 0.81 | DHODH (0.48) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL11410079 | 0.81 | DHODH (0.48) | MEN1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL11418727 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |