Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | LDLR | P01130 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908810 | 0.94 | BLK (0.42) | BLKBTKSRCENPP2KMT2A | |
| SCHEMBL11343129 | 0.83 | PRMT1 (0.44) | SRCENPP2KMT2APOLBIDH1 | |
| SCHEMBL11341737 | 0.83 | TIMP3 (0.50) | ENPP2POLBTIMP3TRPV1HPSE | |
| SCHEMBL10823660 | 0.83 | IDH1 (0.53) | IDH1 | |
| SCHEMBL11417274 | 0.82 | PRMT1 (0.49) | ENPP2KMT2ATIMP3TRPV1MEN1 | |
| SCHEMBL11342069 | 0.81 | ENPP2 (0.43) | BLKBTKENPP2IDH1LDLR | |
| SCHEMBL11341803 | 0.81 | ENPP2 (0.36) | BLKBTKENPP2KMT2ATIMP3 | |
| SCHEMBL11341747 | 0.80 | PRMT1 (0.50) | ENPP2KMT2APOLBTIMP3CA2 | |
| SCHEMBL11336058 | 0.80 | TIMP3 (0.46) | ENPP2KMT2AIDH1TIMP3PPARG | |
| SCHEMBL11341170 | 0.80 | TIMP3 (0.46) | ENPP2KMT2AIDH1TIMP3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216164-A | Ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |