Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11409699 | 0.88 | MAPT (0.48) | EGFRTSHRMAPTRAB9AALDH1A1 | |
| SCHEMBL11416360 | 0.83 | ALDH1A1 (0.55) | EGFRTSHRMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14337485 | 0.82 | MAPT (0.56) | EGFRTSHRMAPTNPC1RAB9A | |
| SCHEMBL28836848 | 0.77 | TSHR (0.65) | TSHRMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11417706 | 0.76 | TSHR (0.54) | EGFRTSHRMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11415311 | 0.75 | TSHR (0.53) | EGFRTSHRMAPTNPC1RAB9A | |
| SCHEMBL11409672 | 0.75 | MAPT (0.48) | MAPTGAAHTTALDH1A1MEN1 | |
| SCHEMBL11409681 | 0.75 | MAPT (0.48) | MAPTGAAHTTALDH1A1MEN1 | |
| SCHEMBL11416429 | 0.75 | TSHR (0.53) | EGFRTSHRMAPTNPC1RAB9A | |
| SCHEMBL28242757 | 0.75 | MAPT (0.46) | MAPTNPC1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230727-A | N-BENZYLIDENEANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1980-10-28 | — | — | US | disclosed |