SCHEMBL14337485

SCHEMBL14337485

CCOC(=O)c1cccc(/C=N/c2ccccc2)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
ALDH1A1 P00352 3/20 0.56
HPGD P15428 2/20 0.56
KDM4E B2RXH2 2/20 0.56
ALOX15 P16050 2/20 0.56
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
EGFR P00533 1/20 0.53
TSHR P16473 1/20 0.51
CDK1 P06493 1/20 0.48
CDK2 P24941 1/20 0.48
MAOB P27338 3/20 0.48
HSD17B10 Q99714 1/20 0.46
POLB P06746 1/20 0.45
TLR2 O60603 1/20 0.44
TLR1 Q15399 1/20 0.44
TLR6 Q9Y2C9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11414939 0.82 EGFR (0.57) MAPTALDH1A1HPGDKDM4EALOX15
SCHEMBL11414936 0.82 EGFR (0.57) MAPTALDH1A1HPGDKDM4EALOX15
SCHEMBL11423945 0.82 EGFR (0.53) MAPTALDH1A1HPGDKDM4EALOX15
SCHEMBL14337136 0.81 MAPT (0.51) MAPTALDH1A1HPGDKDM4EALOX15
SCHEMBL14337415 0.80 SIRT2 (0.50) MAPTALDH1A1HPGDKDM4ERAB9A
SCHEMBL9381488 0.79 CA1 (0.55) MAPTALDH1A1HPGDKDM4EALOX15
SCHEMBL9381486 0.79 CA1 (0.55) MAPTALDH1A1HPGDKDM4EALOX15
SCHEMBL2545430 0.79 GAA (0.49) MAPTALDH1A1HPGDKDM4EALOX15
SCHEMBL2545435 0.79 GAA (0.49) MAPTALDH1A1HPGDKDM4EALOX15
SCHEMBL14337134 0.77 SIRT2 (0.46) MAPTALDH1A1HPGDKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170308-B1 Process for producing a copolymer of a non-polar olefin and a polar olefin MITSUI CHEMICALS INC (JP) 2015-05-06 EP disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed