Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431617 | 0.95 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9ACASP6 | |
| SCHEMBL10908133 | 0.93 | MEN1 (0.64) | KMT2AMEN1NPC1RAB9ACASP6 | |
| SCHEMBL11431595 | 0.88 | CASP6 (0.71) | KMT2AMEN1NPC1RAB9ACASP6 | |
| SCHEMBL11426033 | 0.87 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11766331 | 0.86 | RAB9A (0.55) | KMT2AMEN1NPC1RAB9ACTDSP1 | |
| SCHEMBL11765604 | 0.85 | KMT2A (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11138083 | 0.85 | RAB9A (0.55) | KMT2AMEN1NPC1RAB9ACTDSP1 | |
| SCHEMBL11421997 | 0.84 | RAB9A (0.59) | KMT2AMEN1NPC1RAB9ACTDSP1 | |
| SCHEMBL11422759 | 0.83 | PRMT1 (0.76) | KMT2AMEN1CASP6CTDSP1PRMT1 | |
| SCHEMBL10909338 | 0.83 | CASP6 (0.67) | KMT2AMEN1CASP6CTDSP1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |
| US-4163675-A | CONTAINING NAPHTHALENE DERIVATIVES | PILOT INK CO., LTD. (JP) | 1979-08-07 | — | — | US | disclosed |