Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12101207 | 0.90 | AOC3 (0.60) | SLC6A4SLC6A2SLC6A3RECQLTDP1 | |
| SCHEMBL412315 | 0.90 | AOC3 (0.60) | SLC6A4SLC6A2SLC6A3RECQLTDP1 | |
| Hydrochloric Acid SCHEMBL440344 | 0.88 | AOC3 (0.59) | SLC6A4SLC6A2SLC6A3RECQLTDP1 | |
| SCHEMBL2608968 | 0.87 | MEN1 (0.52) | TAAR1SLC6A4SLC6A2SLC6A3KMT2A | |
| SCHEMBL10931500 | 0.86 | MEN1 (0.51) | TAAR1SLC6A4SLC6A2SLC6A3KMT2A | |
| SCHEMBL7898797 | 0.85 | CYP3A4 (0.54) | SLC6A2SLC6A3KMT2AMEN1AOC3 | |
| SCHEMBL4776996 | 0.82 | TAAR1 (0.53) | TAAR1SLC6A4SLC6A2SLC6A3KDM4E | |
| SCHEMBL12261670 | 0.82 | TAAR1 (0.53) | TAAR1SLC6A4SLC6A2SLC6A3KDM4E | |
| SCHEMBL16325098 | 0.82 | TAAR1 (0.56) | TAAR1SLC6A4SLC6A2SLC6A3KDM4E | |
| SCHEMBL29664492 | 0.82 | KMT2A (0.54) | TAAR1SLC6A4SLC6A2SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130253061-A1 | METHOD OF DROXIDOPA SYNTHESIS | CHELSEA THERAPEUTICS, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-4226803-A | Process for production of optically active bases | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253061-A1 | METHOD OF DROXIDOPA SYNTHESIS | DDO, DAO, COMT | TAAR1 2614/4885SLC6A4 135/4885SLC6A2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.