Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.37 |
| ▸ | CHAT | P28329 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10256796 | 0.98 | CHAT (0.47) | CHATACHEBCHEADORA3MAOA | |
| Iodide SCHEMBL11591341 | 0.96 | CHAT (0.46) | CHATACHEBCHEADORA3GRIN1 | |
| SCHEMBL14419209 | 0.80 | CHAT (0.43) | CHATACHEBCHEADORA3MAOA | |
| SCHEMBL5306354 | 0.79 | CHAT (0.50) | CHATACHEBCHEMAOAMAOB | |
| SCHEMBL12132102 | 0.74 | CCR9 (0.35) | — | |
| SCHEMBL10144617 | 0.74 | ALDH1A1 (0.34) | CHAT | |
| SCHEMBL19458284 | 0.74 | CHRNA7 (0.34) | MAOAMAOBGRIN1GRIN2AGRIN2B | |
| Sulcatin SCHEMBL2040356 | 0.72 | USP2 (0.39) | CHATACHEBCHEADORA3HDAC8 | |
| SCHEMBL10764076 | 0.71 | CA2 (0.35) | — | |
| SCHEMBL5297606 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228230-A | Ultrasonic imaging of internally fogged silver halide elements | EASTMAN KODAK COMPANY (US) | 1980-10-14 | — | — | US | disclosed |