Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 3/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422649 | 0.93 | PGR (0.62) | PGRHIF1ANR3C1CYP3A4LMNA | |
| SCHEMBL11421536 | 0.91 | PGR (0.76) | PGRHIF1ANR3C1CYP3A4LMNA | |
| SCHEMBL11422613 | 0.90 | PGR (0.67) | PGRHIF1ANR3C1CYP3A4LMNA | |
| SCHEMBL11431394 | 0.89 | PGR (0.68) | PGRHIF1ANR3C1CYP3A4LMNA | |
| SCHEMBL11422610 | 0.88 | PGR (0.65) | PGRHIF1ANR3C1CYP3A4LMNA | |
| SCHEMBL11424511 | 0.88 | PGR (0.82) | PGRHIF1ANR3C1CYP3A4LMNA | |
| SCHEMBL11430257 | 0.87 | PGR (0.56) | PGRHIF1ANR3C1CYP3A4LMNA | |
| SCHEMBL11438794 | 0.87 | PGR (0.55) | PGRHIF1ANR3C1CYP3A4LMNA | |
| SCHEMBL7094754 | 0.86 | CYP3A4 (0.65) | PGRHIF1ANR3C1CYP3A4LMNA | |
| SCHEMBL10905048 | 0.86 | NR3C1 (0.69) | PGRHIF1ANR3C1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |