Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15856172 | 0.78 | TAAR1 (0.39) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL17611046 | 0.78 | MAOB (0.40) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL30085317 | 0.78 | APLNR (0.49) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL3699138 | 0.78 | NOS3 (0.42) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL27961890 | 0.78 | TAAR1 (0.39) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL20470389 | 0.78 | APLNR (0.49) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL2897054 | 0.76 | ESR1 (0.50) | HTR3AESR1ESR2GRIN2BMEN1 | |
| SCHEMBL24298150 | 0.74 | TAAR1 (0.36) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL15466330 | 0.74 | KCNJ1 (0.40) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL30085323 | 0.74 | KCNJ1 (0.40) | TAAR1HTR3ATSHRNFKB1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260619-A | ANTIISCHEMIC | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-3952101-A | BETA ADRENERGIC STIMULANT | SMITHKLINE CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |
| US-3952101-A | BETA ADRENERGIC STIMULANT | SMITHKLINE CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |
| US-3952101-A | BETA ADRENERGIC STIMULANT | SMITHKLINE CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |