Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422006 | 0.92 | KCNMA1 (0.49) | KCNMA1USP2CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL11425400 | 0.87 | KCNMA1 (0.47) | KCNMA1USP2SMN1; SMN2MAPTMEN1 | |
| SCHEMBL11430247 | 0.86 | KCNMA1 (0.47) | KCNMA1SIRT6USP2CRHBPCRHR2 | |
| SCHEMBL11430401 | 0.86 | KCNMA1 (0.51) | KCNMA1SIRT6CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL11425946 | 0.85 | RAB9A (0.43) | SMN1; SMN2MAPTMEN1LMNAKMT2A | |
| SCHEMBL11425185 | 0.85 | KCNMA1 (0.46) | KCNMA1SIRT6CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL11433946 | 0.84 | KCNMA1 (0.52) | KCNMA1SIRT6USP2CRHBPCRHR2 | |
| SCHEMBL11424281 | 0.84 | KCNMA1 (0.49) | KCNMA1SIRT6USP2CRHBPCRHR2 | |
| SCHEMBL11433794 | 0.84 | KCNMA1 (0.49) | KCNMA1SIRT6USP2CRHBPCRHR2 | |
| SCHEMBL11425170 | 0.84 | MAPT (0.53) | SMN1; SMN2MAPTMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |