Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | CD40 | P25942 | 1/20 | 0.48 |
| ▸ | CD40LG | P29965 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439163 | 0.96 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11425397 | 0.92 | ALDH1A1 (0.48) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11442251 | 0.88 | ALDH1A1 (0.48) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11422002 | 0.87 | ALDH1A1 (0.60) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11431789 | 0.85 | HPGD (0.60) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11426103 | 0.84 | CD40 (0.66) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11426200 | 0.83 | MEN1 (0.46) | SMN1; SMN2MEN1KMT2ARAB9AHPGD | |
| SCHEMBL11423101 | 0.83 | ALDH1A1 (0.60) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11437122 | 0.83 | HPGD (0.66) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11431309 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |