Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 3/20 | 0.66 |
| ▸ | CD40LG | P29965 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431130 | 0.95 | CD40 (0.66) | CD40CD40LGMAPTRAB9ANPC1 | |
| SCHEMBL11433874 | 0.88 | KMT2A (0.56) | CD40CD40LGMAPTRAB9ANPC1 | |
| SCHEMBL11500547 | 0.85 | CD40 (0.61) | CD40CD40LGMAPTRAB9ANPC1 | |
| SCHEMBL11425397 | 0.84 | ALDH1A1 (0.48) | CD40CD40LGMAPTRAB9ANPC1 | |
| SCHEMBL11425278 | 0.84 | SMN1; SMN2 (0.56) | CD40CD40LGMAPTRAB9ANPC1 | |
| SCHEMBL11425321 | 0.84 | KMT2A (0.56) | CD40CD40LGMAPTRAB9ANPC1 | |
| SCHEMBL11427485 | 0.83 | CASP6 (0.48) | CD40CD40LGMAPTHTTHPGD | |
| SCHEMBL11347634 | 0.82 | TIMP3 (0.61) | CD40CD40LGMAPTALDH1A1MEN1 | |
| SCHEMBL10905173 | 0.82 | TIMP3 (0.53) | CD40CD40LGMAPTHTTALDH1A1 | |
| SCHEMBL11423070 | 0.82 | CD40 (0.66) | CD40CD40LGMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |