Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432089 | 0.92 | KCNMA1 (0.43) | KCNMA1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11433703 | 0.86 | TNF (0.48) | KCNMA1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11428750 | 0.85 | NT5E (0.55) | KCNMA1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11421866 | 0.84 | KCNMA1 (0.46) | KCNMA1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11208452 | 0.84 | NT5E (0.54) | KCNMA1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11432113 | 0.84 | MAPT (0.43) | KCNMA1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11435637 | 0.83 | NPC1 (0.45) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL11427501 | 0.83 | NPC1 (0.45) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL11423194 | 0.82 | KCNMA1 (0.51) | KCNMA1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11437160 | 0.82 | KCNMA1 (0.45) | KCNMA1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |