Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426299 | 0.92 | KCNMA1 (0.45) | KCNMA1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11438365 | 0.86 | TNF (0.45) | KCNMA1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11427501 | 0.85 | NPC1 (0.45) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL11431542 | 0.85 | NT5E (0.55) | KCNMA1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11434202 | 0.84 | KCNMA1 (0.43) | KCNMA1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11215156 | 0.84 | NT5E (0.54) | KCNMA1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11425750 | 0.84 | KMT2A (0.42) | KCNMA1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11432085 | 0.84 | MEN1 (0.55) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL11426457 | 0.82 | KCNMA1 (0.48) | KCNMA1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11423041 | 0.82 | KCNMA1 (0.40) | KCNMA1RAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |