Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426110 | 0.93 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11423135 | 0.92 | POLB (0.51) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11422986 | 0.86 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11437157 | 0.86 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11428748 | 0.85 | NT5E (0.55) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11421985 | 0.85 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11424230 | 0.84 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11430233 | 0.84 | POLB (0.52) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11433072 | 0.84 | CASP6 (0.48) | CTDSP1ALDH1A1MAPTMAOAMAOB | |
| SCHEMBL11442275 | 0.84 | RAB9A (0.55) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |