Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431322 | 0.88 | PKM (0.50) | EPHX2MEN1KMT2AATMRAB9A | |
| SCHEMBL11411090 | 0.85 | POLB (0.54) | EPHX2MEN1KMT2ARAB9APKM | |
| SCHEMBL11432520 | 0.85 | PKM (0.62) | EPHX2MEN1KMT2AATMRAB9A | |
| SCHEMBL11440703 | 0.84 | MEN1 (0.52) | EPHX2MEN1KMT2AATMRAB9A | |
| SCHEMBL11423498 | 0.83 | PKM (0.51) | MEN1KMT2AATMRAB9APKM | |
| SCHEMBL11419842 | 0.82 | KMT2A (0.51) | EPHX2MEN1KMT2AEPHX1MTNR1A | |
| SCHEMBL25085625 | 0.80 | HDAC1 (0.55) | RAB9APKMPOLBMAPTCTDSP1 | |
| SCHEMBL13826300 | 0.79 | GAA (0.55) | MEN1KMT2APKMPOLBCTDSP1 | |
| SCHEMBL13536979 | 0.79 | KDM4E (0.55) | RAB9APKMPOLBCTDSP1TDP1 | |
| SCHEMBL11408715 | 0.78 | PKM (0.56) | EPHX2MEN1KMT2AATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183956-A | Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-01-15 | — | — | US | disclosed |