Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180242 | 0.87 | SMN1; SMN2 (0.51) | PKMSMN1; SMN2ALDH1A1RECQLGAA | |
| SCHEMBL11431322 | 0.86 | PKM (0.50) | PKMPOLBCTDSP1TDP1SMN1; SMN2 | |
| SCHEMBL25085625 | 0.83 | HDAC1 (0.55) | PKMPOLBCTDSP1TDP1SMN1; SMN2 | |
| SCHEMBL11423764 | 0.83 | SMN1; SMN2 (0.48) | PKMPOLBSMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL11426601 | 0.83 | EPHX2 (0.53) | PKMPOLBCTDSP1TDP1RAB9A | |
| SCHEMBL13826300 | 0.83 | GAA (0.55) | PKMPOLBCTDSP1TDP1ALDH1A1 | |
| SCHEMBL11419588 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1RECQLMAPTLMNA | |
| SCHEMBL11322116 | 0.81 | MAP2K2 (0.46) | PKMPOLBCTDSP1TDP1SMN1; SMN2 | |
| SCHEMBL11420427 | 0.81 | POLB (0.47) | PKMPOLBSMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL11426554 | 0.80 | RAB9A (0.63) | PKMPOLBSMN1; SMN2ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183956-A | Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-01-15 | — | — | US | disclosed |