Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 10/20 | 0.98 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.98 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.98 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.98 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.98 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.98 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.50 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.50 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.50 |
| ▸ | YEATS2 | Q9ULM3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11430312 | 0.99 | ADRA1D (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11432246 | 0.98 | ADRA1D (0.98) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL11428029 | 0.92 | ADRA1A (0.83) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL11443026 | 0.89 | ADRA1D (0.98) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL11441354 | 0.89 | ADRA1D (0.79) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11427722 | 0.89 | ADRA1D (1.00) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11439279 | 0.88 | ADRA1D (0.85) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL11427976 | 0.88 | ADRA1D (0.77) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11032271 | 0.88 | ADRA1A (0.80) | ADRA1AADRA1DADRA1BADRB2ADRB1 | |
| SCHEMBL11437489 | 0.87 | ADRA1D (0.98) | ADRA1AADRA1DADRA1BADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200755-A | ADRENERGIC BLOCKING AGENTS, ANTISPASMODIC AGENTS, HYPOTENSIVE AGENTS | RICHARDSON-MERRELL INC. (US) | 1980-04-29 | — | — | US | claimed |
| US-4200755-A | ADRENERGIC BLOCKING AGENTS, ANTISPASMODIC AGENTS, HYPOTENSIVE AGENTS | RICHARDSON-MERRELL INC. (US) | 1980-04-29 | — | — | US | disclosed |