Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593098 | 0.91 | LMNA (0.34) | AOC3SMN1; SMN2FFAR1GPR84POLB | |
| SCHEMBL28286989 | 0.86 | AOC3 (0.35) | AOC3SMN1; SMN2FFAR1GPR84 | |
| SCHEMBL3712831 | 0.82 | AOC3 (0.36) | AOC3SMN1; SMN2FFAR1GPR84POLB | |
| SCHEMBL2231032 | 0.81 | LMNA (0.39) | AOC3GPR84TP53ESR1LMNA | |
| SCHEMBL21516482 | 0.80 | SMN1; SMN2 (0.38) | AOC3SMN1; SMN2FFAR1GPR84POLB | |
| SCHEMBL27932074 | 0.78 | CSNK1E (0.38) | OPRM1OPRD1OPRK1OPRL1ESR1 | |
| SCHEMBL28871426 | 0.75 | ALDH1A1 (0.35) | POLBOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL27497906 | 0.74 | LMNA (0.34) | TP53LMNA | |
| SCHEMBL28076752 | 0.74 | CSNK1E (0.39) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL27948076 | 0.72 | AOC3 (0.33) | AOC3SMN1; SMN2FFAR1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225497-A | ACID CATALYSTS FOR IMIDATION | RHONE-POULENC INDUSTRIES (FR) | 1980-09-30 | — | — | US | claimed |
| US-4225497-A | ACID CATALYSTS FOR IMIDATION | RHONE-POULENC INDUSTRIES (FR) | 1980-09-30 | — | — | US | disclosed |