Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009777 | 0.83 | SRC (0.38) | SRCLMNACYP2D6 | |
| SCHEMBL9157493 | 0.81 | HDAC3 (0.47) | CA1CA2ALDH1A1LMNAHPGD | |
| SCHEMBL241909 | 0.80 | SRC (0.56) | SRCTDP1CYP2C19LMNACES2 | |
| SCHEMBL28232530 | 0.80 | SRC (0.56) | SRCTDP1CYP2C19LMNACES2 | |
| SCHEMBL28232476 | 0.80 | SRC (0.56) | SRCTDP1CYP2C19LMNACES2 | |
| SCHEMBL2893282 | 0.79 | TPMT (0.44) | SRCCA1CA2CYP2D6 | |
| SCHEMBL2399005 | 0.79 | KEAP1 (0.53) | ALDH1A1CYP2C19LMNACES2SRD5A2 | |
| SCHEMBL11405448 | 0.79 | CYP2C9 (0.46) | KMT2ATDP1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11254414 | 0.79 | POLB (0.41) | SRCCA3CA14CA6ALDH1A1 | |
| SCHEMBL28140063 | 0.79 | CYP2C9 (0.48) | CA12CA1CA2TYRCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482832-A1 | 5-[7-(3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBONYL)-1,2,3,4 TETRAHYDROISOQUINOLIN-6-Y L]-1H-PYRROLE-3-CARBOXAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | Les Laboratoires Servier (FR) | 2025-01-01 | — | — | EP | disclosed |
| CN-119053587-A | 5- [7- (3, 4-Dihydro-1H-isoquinoline-2-carbonyl) -1,2,3,4 tetrahydroisoquinolin-6-yl ] -1H-pyrrole-3-carboxamide derivatives, pharmaceutical compositions containing same and use thereof as pro-apoptotic agents | 法国施维雅药厂 | 2024-11-29 | — | — | CN | disclosed |
| WO-2023161317-A1 | 5-[7-(3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBONYL)-1,2,3,4 TETRAHYDROISOQUINOLIN-6-Y L]-1H-PYRROLE-3-CARBOXAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | LES LABORATOIRES SERVIER (FR) | 2023-08-31 | — | — | WO | disclosed |
| CN-104231070-B | Glucose-dependent-insulinotropic polypeptide terminal modified N（GIP）Analog | 益普生制药股份有限公司 | 2017-09-01 | — | — | CN | disclosed |
| CN-104031140-B | Truncated analogues of glucose-dependent insulinotropic polypeptide | 益普生制药股份有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-105601905-A | Preparation method and application of polymer additive | JIANGSU SUBOTE NEW MAT CO LTD | 2016-05-25 | — | — | CN | disclosed |
| CN-103221437-B | Polymer compound and resist protective film composition for liquid immersion exposure process containing same | DONGJIN SEMICHEM CO.,LTD. (KR) | 2016-02-17 | — | — | CN | disclosed |
| CN-105164586-A | Composition for forming resist protective film for lithography and method for forming pattern of semiconductor element using same | DONGJIN SEMICHEM CO LTD | 2015-12-16 | — | — | CN | disclosed |
| CN-104829706-A | Analogues of glucose-dependent insulinotropic polypeptide | IPSEN PHARMA SAS | 2015-08-12 | — | — | CN | disclosed |
| CN-102171244-B | Analogues of glucose-dependent insulinotropic peptide | IPSEN PHARMA SAS | 2015-05-13 | — | — | CN | disclosed |
| CN-104231070-A | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | IPSEN PHARMA SAS | 2014-12-24 | — | — | CN | disclosed |
| CN-104086530-A | 4-substituted quinoline compounds and applications thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-10-08 | — | — | CN | disclosed |
| CN-104031140-A | Truncated analogues of glucose-dependent insulinotropic polypeptide | IPSEN PHARMA SAS | 2014-09-10 | — | — | CN | disclosed |
| CN-103641906-A | Glucose-dependent insulinotropic polypeptide analogues | IPSEN PHARMA SAS | 2014-03-19 | — | — | CN | disclosed |
| US-8303844-B2 | Benzo[f]chrome any pyrano[3,2-f]chrome derivatives for use in liquid crystal media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20110043746-A1 | BENZO[F]CHROME ANY PYRANO[3,2-F]CHROME DERIVATIVES FOR USE IN LIQUID CRYSTAL MEDIA | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-02-24 | — | — | US | disclosed |
| CN-1898222-A | Substituted aryl cycloalkanol derivatives and methods of their use | WYETH CORP (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1897950-A | Fused aryl and heteroaryl derivatives and methods of use thereof | WYETH CORP (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1882524-A | 4- ((phenoxyalkyl) thio) -phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA NV (BE) | 2006-12-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110043746-A1 | BENZO[F]CHROME ANY PYRANO[3,2-F]CHROME DERIVATIVES FOR USE IN LIQUID CRYSTAL MEDIA | CHRM1, F12, CTRB2 | SRC 1529/4885ESR1 360/4885ESR2 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.