Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 1/20 | 0.42 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428153 | 1.00 | CA12 (0.46) | CA12CA2CA9GRIN2DGRIN3B | |
| SCHEMBL9273922 | 0.86 | CA12 (0.68) | CA12CA2CA9L3MBTL1ALDH1A1 | |
| SCHEMBL9273920 | 0.86 | CA12 (0.68) | CA12CA2CA9L3MBTL1ALDH1A1 | |
| SCHEMBL11405757 | 0.86 | CA12 (0.50) | CA12CA2CA9GRIN2DGRIN3B | |
| SCHEMBL11405759 | 0.86 | CA12 (0.50) | CA12CA2CA9GRIN2DGRIN3B | |
| SCHEMBL11404085 | 0.85 | L3MBTL1 (0.50) | CA12CA2CA9L3MBTL1NPSR1 | |
| SCHEMBL11404083 | 0.85 | L3MBTL1 (0.50) | CA12CA2CA9L3MBTL1NPSR1 | |
| SCHEMBL11402313 | 0.81 | ALDH1A1 (0.52) | CA12CA2CA9GRIN2DGRIN3B | |
| SCHEMBL11402317 | 0.81 | ALDH1A1 (0.52) | CA12CA2CA9GRIN2DGRIN3B | |
| SCHEMBL11420736 | 0.81 | MAPT (0.46) | CA12CA2CA9GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235929-A | TOPICAL ADMINISTRATION OF ANTIINFLAMMATORY AGENT | WILLIAM H. RORER, INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4176198-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |