Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 2/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | CD40 | P25942 | 2/20 | 0.44 |
| ▸ | CD40LG | P29965 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433078 | 0.95 | AURKB (0.52) | AURKBAURKATIMP3MEN1KMT2A | |
| SCHEMBL11429278 | 0.91 | AURKA (0.50) | AURKBAURKATIMP3MEN1KMT2A | |
| SCHEMBL11758756 | 0.89 | TIMP3 (0.54) | AURKBAURKATIMP3MEN1KMT2A | |
| SCHEMBL1413171 | 0.89 | AURKB (0.52) | AURKBAURKATIMP3MEN1KMT2A | |
| SCHEMBL11209218 | 0.88 | AURKB (0.53) | AURKBAURKATIMP3MEN1KMT2A | |
| SCHEMBL11582287 | 0.87 | AURKB (0.52) | AURKBAURKATIMP3MEN1KMT2A | |
| SCHEMBL10908486 | 0.87 | TIMP3 (0.55) | AURKBAURKATIMP3MEN1KMT2A | |
| SCHEMBL11338955 | 0.87 | TIMP3 (0.64) | AURKBAURKATIMP3MEN1KMT2A | |
| SCHEMBL11436491 | 0.85 | HDAC1 (0.46) | AURKBAURKATIMP3MEN1KMT2A | |
| SCHEMBL11427718 | 0.85 | HDAC1 (0.46) | AURKBAURKATIMP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |