SCHEMBL11428293

SCHEMBL11428293

CCCCC(CC)Cn1c(O)cc(C)c(CC)c1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.36
MAPT P10636 2/20 0.35
TP53 P04637 2/20 0.35
ALDH1A1 P00352 7/20 0.33
KDM4E B2RXH2 4/20 0.33
HPGD P15428 4/20 0.33
GAA P10253 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPK1 P28482 2/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
LMNA P02545 3/20 0.32
CA2 P00918 3/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
XBP1 P17861 1/20 0.32
PPARG P37231 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11236043 0.92 ALDH1A1 (0.37) BCL2L1MAPTTP53ALDH1A1KDM4E
SCHEMBL11241059 0.86 BCL2L1 (0.37) BCL2L1MAPTTP53ALDH1A1KDM4E
SCHEMBL11437527 0.85 KDM4E (0.45) MAPTTP53ALDH1A1KDM4EHPGD
SCHEMBL4266313 0.83 KDM4E (0.48) MAPTALDH1A1KDM4EHPGDGAA
SCHEMBL4266944 0.81 BCL2L1 (0.38) BCL2L1MAPTTP53ALDH1A1KDM4E
SCHEMBL11241641 0.79 ALDH1A1 (0.46) MAPTALDH1A1KDM4EHPGDGAA
SCHEMBL4271188 0.77 BCL2L1 (0.38) BCL2L1TP53LMNAKMT2AMEN1
SCHEMBL11433462 0.76 KDM4E (0.42) MAPTTP53ALDH1A1KDM4EHPGD
SCHEMBL11436051 0.76 KDM4E (0.42) MAPTTP53ALDH1A1KDM4EHPGD
SCHEMBL30982493 0.76 BCL2L1 (0.39) BCL2L1MAPTTP53ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4225491-A REACTIVE DYES FOR COTTON ICI UNITED STATES, INC. (US) 1980-09-30 US disclosed