SCHEMBL4266313

SCHEMBL4266313

CCCCC(CC)Cn1c(O)cc(C)c(C#N)c1=O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.48
USP2 O75604 1/20 0.48
LMNA P02545 3/20 0.47
ALDH1A1 P00352 6/20 0.44
MAPT P10636 4/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
MAPK1 P28482 2/20 0.44
GAA P10253 2/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
KMT2A Q03164 7/20 0.44
MEN1 O00255 6/20 0.44
THRB P10828 1/20 0.44
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 1/20 0.36
UPP1 Q16831 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11637890 0.88 KDM4E (0.59) KDM4EUSP2LMNAALDH1A1MAPT
SCHEMBL11241059 0.85 BCL2L1 (0.37) KDM4ELMNAALDH1A1MAPTHPGD
SCHEMBL10891158 0.85 KDM4E (0.64) KDM4EUSP2LMNAALDH1A1MAPT
SCHEMBL11236043 0.83 ALDH1A1 (0.37) KDM4EUSP2LMNAALDH1A1MAPT
SCHEMBL11428293 0.83 BCL2L1 (0.36) KDM4ELMNAALDH1A1MAPTHPGD
SCHEMBL4579017 0.82 KDM4E (0.43) KDM4EUSP2LMNAALDH1A1MAPT
SCHEMBL4266944 0.80 BCL2L1 (0.38) KDM4ELMNAALDH1A1MAPTHPGD
SCHEMBL623429 0.79 KDM4E (0.60) KDM4EUSP2LMNAALDH1A1MAPT
SCHEMBL11129423 0.78 KDM4E (0.59) KDM4EUSP2LMNAALDH1A1MAPT
SCHEMBL8796572 0.78 ALDH1A1 (0.45) KDM4ELMNAALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2864423-B1 ELECTROPHORETIC FLUID E INK CORP (US) 2023-06-07 EP disclosed
WO-2020218297-A1 POLYMETHINE COMPOUND 株式会社ADEKA 2020-10-29 WO disclosed
CN-108047749-B Colored resin composition, color filter, liquid crystal display device, and organic EL display device 三菱化学株式会社 2020-06-19 CN disclosed
US-9811014-B2 Yellow toner and production method therefor CANON KABUSHIKI KAISHA (JP) 2017-11-07 US disclosed
US-9811014-B2 Yellow toner and production method therefor CANON KABUSHIKI KAISHA (JP) 2017-11-07 US disclosed
US-9297940-B2 Photosensitive resin composition and color filter prepared using the same CHEIL INDUSTRIES INC. (KR) 2016-03-29 US disclosed
US-20150378273-A1 YELLOW TONER AND PRODUCTION METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2015-12-31 US disclosed
US-20150378273-A1 YELLOW TONER AND PRODUCTION METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2015-12-31 US disclosed
WO-2015122567-A1 NOVEL DYE COMPOUND, PHOTOSENSITIVE RESIN COMPOSITION COMPRISING SAME, AND COLOUR FILTER 제일모직 주식회사 2015-08-20 WO disclosed
US-20150177587-A1 ELECTROPHORETIC FLUID E INK CORPORATION 2015-06-25 US disclosed
US-6060206-A Photo- and heat-sensitive recording material and colorant produced from the material FUJI PHOTO FILM CO., LTD. (JP) 2000-05-09 US disclosed
US-6017672-A MIXTURE OF DIAZONIUM SALT HAVING ABSORPTION WAVELENGTH SHORTER THAN 350 NANOMETERS AND A THERMALLY REACTIVE COUPLER CONTAINED WITHIN RECORDING LAYER COATED ONTO SUPPORT; STORAGE STABILITY, PHOTOSTABILITY, HIGH COLOR DENSITY FUJI PHOTO FILM CO., LTD. (JP) 2000-01-25 US disclosed
US-5998082-A DIHYDROCARBYLOXYPHENYL DIAZONIUM COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-12-07 US disclosed
US-5925489-A CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1999-07-20 US disclosed
EP-0827020-A1 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-03-04 EP disclosed
EP-0109527-A1 Water-insoluble monoazo dyestuffs, methods for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1984-05-30 EP disclosed
US-4225491-A REACTIVE DYES FOR COTTON ICI UNITED STATES, INC. (US) 1980-09-30 US disclosed
US-4144231-A Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4143033-A WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4137228-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed