Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426704 | 0.92 | BRD9 (0.43) | PGRBRD9AKR1C3AKR1C2TGFBR1 | |
| SCHEMBL11433951 | 0.92 | BRD9 (0.46) | PGRBRD9MAPTAKR1C3AKR1C2 | |
| SCHEMBL11435975 | 0.90 | BRD9 (0.42) | BRD9AKR1C3AKR1C2TGFBR1ALOX15 | |
| Fluridone SCHEMBL6751451 | 0.90 | BRD9 (0.43) | BRD9MAPTAKR1C3AKR1C2TGFBR1 | |
| Fluridone SCHEMBL54579 | 0.90 | BRD9 (0.43) | BRD9MAPTAKR1C3AKR1C2TGFBR1 | |
| SCHEMBL11434477 | 0.89 | MAPT (0.45) | PGRBRD9MAPTTGFBR1PARP10 | |
| SCHEMBL11442564 | 0.88 | KDM4E (0.42) | PGRBRD9AKR1C3AKR1C2TGFBR1 | |
| SCHEMBL11441223 | 0.88 | ALOX15 (0.44) | PGRBRD9MAPTMAPK1AKR1C3 | |
| SCHEMBL11178917 | 0.88 | NPC1 (0.44) | PGRBRD9MAPTTGFBR1PARP10 | |
| SCHEMBL11428028 | 0.86 | NR1H4 (0.49) | MAPTAKR1C3AKR1C2ALOX12TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | claimed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | claimed |
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4102669-A | IN COTTON CULTURE | ELI LILLY AND COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4065290-A | Herbicidal β-phenyl-4-piperidinones | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |