Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429556 | 0.91 | MAPT (0.47) | RORCRORBHTTCYP1A2CYP3A4 | |
| SCHEMBL11426704 | 0.91 | BRD9 (0.43) | RORCRORBKDM4EBRD9TGFBR1 | |
| SCHEMBL11433951 | 0.90 | BRD9 (0.46) | RORCRORBKDM4EMAPTBRD9 | |
| SCHEMBL11431587 | 0.90 | MAPT (0.43) | RORCRORBHTTCYP1A2CYP3A4 | |
| Fluridone SCHEMBL54579 | 0.89 | BRD9 (0.43) | NPC1RAB9ARORCRORBLMNA | |
| Fluridone SCHEMBL6751451 | 0.89 | BRD9 (0.43) | NPC1RAB9ARORCRORBLMNA | |
| SCHEMBL11436424 | 0.88 | RORB (0.44) | RORCRORBMAPTBRD9NPSR1 | |
| SCHEMBL11434477 | 0.88 | MAPT (0.45) | NPC1RAB9ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11428587 | 0.88 | PGR (0.43) | MAPTBRD9TGFBR1PARP10PARP11 | |
| SCHEMBL11436515 | 0.88 | DPP4 (0.43) | RORCRORBHTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | claimed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | claimed |
| EP-0006359-B1 | USE OF 1-ALKYL-3-PHENYLPYRIDINIUM SALTS AS HERBICIDES AND HERBICIDAL FORMULATIONS CONTAINING THE SALTS | ELI LILLY AND COMPANY (US) | 1983-09-28 | — | — | EP | disclosed |
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4218238-A | Herbicidal 1-alkyl-3-phenylpyridinium salts | ELI LILLY AND COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| EP-0006359-A1 | Use of 1-alkyl-3-phenylpyridinium salts as herbicides and herbicidal formulations containing the salts | ELI LILLY AND COMPANY (US) | 1980-01-09 | — | — | EP | disclosed |
| US-4174209-A | Herbicidal 1-alkyl-3-phenylpyridinium salts | ELI LILLY AND COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4102669-A | IN COTTON CULTURE | ELI LILLY AND COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4065290-A | Herbicidal β-phenyl-4-piperidinones | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |