Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | CD40 | P25942 | 2/20 | 0.40 |
| ▸ | CD40LG | P29965 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440900 | 0.92 | KDR (0.43) | KDRCD40CD40LGRAB9ANPC1 | |
| SCHEMBL11433578 | 0.87 | CD40 (0.42) | KDRCD40CD40LGRAB9AKMT2A | |
| SCHEMBL11424309 | 0.86 | KCNMA1 (0.46) | KDRCD40CD40LGRAB9ANPC1 | |
| SCHEMBL11430987 | 0.85 | KDR (0.40) | KDRCD40CD40LGRAB9ANPC1 | |
| SCHEMBL11427943 | 0.84 | RAB9A (0.43) | KDRCD40CD40LGRAB9ANPC1 | |
| SCHEMBL11423102 | 0.84 | KCNMA1 (0.48) | KDRCD40CD40LGRAB9ANPC1 | |
| SCHEMBL11433192 | 0.83 | AURKA (0.43) | KDRRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL11426339 | 0.83 | AURKB (0.52) | KDRRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL11428597 | 0.83 | CD40 (0.45) | KDRCD40CD40LGRAB9ANPC1 | |
| SCHEMBL11427850 | 0.83 | AURKA (0.43) | KDRRAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |