Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 3/20 | 0.34 |
| ▸ | MAX | P61244 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677491 | 0.79 | SCN4A (0.39) | SMN1; SMN2MAPTCYP2D6CYP2C9MEN1 | |
| SCHEMBL27493752 | 0.77 | CYP19A1 (0.39) | NPC1RAB9AMAPTMAPK1CHRNB2 | |
| SCHEMBL4252795 | 0.76 | TDP1 (0.40) | SMN1; SMN2MAPTMEN1LMNAHTT | |
| SCHEMBL11241339 | 0.75 | CA12 (0.34) | NPC1RAB9AMAPTRECQLCHRNB2 | |
| SCHEMBL28657269 | 0.75 | PIN1 (0.42) | NPC1RAB9AMAPTMEN1LMNA | |
| SCHEMBL28195096 | 0.73 | SCN4A (0.35) | SMN1; SMN2MAPTCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7015864 | 0.73 | TLR4 (0.48) | SMN1; SMN2NPC1RAB9AMAPTPOLB | |
| SCHEMBL11113662 | 0.72 | PRMT5 (0.44) | SMN1; SMN2MAPTMEN1LMNAKMT2A | |
| SCHEMBL29070974 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL17164316 | 0.71 | SCN4A (0.34) | SMN1; SMN2MAPTCYP2D6CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182915-A | PHENOL FROM BENZENE BY REACTION OF THALLIUM/III/ METALLATE WITH HYDROXYL DONOR | HALCON INTERNATIONAL, INC. (US) | 1980-01-08 | — | — | US | disclosed |