Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677039 | 0.80 | TSHR (0.46) | MAPTTSHRLTA4HLMNATP53 | |
| SCHEMBL3597737 | 0.78 | TSHR (0.49) | MAPTTSHRLTA4HLMNATP53 | |
| SCHEMBL1451918 | 0.78 | TSHR (0.49) | MAPTTSHRLTA4HLMNATP53 | |
| SCHEMBL5983957 | 0.78 | TSHR (0.49) | MAPTTSHRLTA4HLMNATP53 | |
| SCHEMBL4252795 | 0.75 | TDP1 (0.40) | MAPTACHETSHRLMNA | |
| SCHEMBL677726 | 0.74 | LTA4H (0.45) | CYP19A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL3794039 | 0.74 | KCNH2 (0.40) | — | |
| SCHEMBL11589552 | 0.74 | SMN1; SMN2 (0.41) | MAPTTSHRLTA4HLMNATP53 | |
| SCHEMBL27581581 | 0.71 | NR5A1 (0.47) | MAPTTSHRLTA4HLMNATP53 | |
| SCHEMBL27373768 | 0.70 | POLB (0.39) | MAPTNPC1ACHELMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1224598-C | Naphthalene derivatives | NOVARTIS AG (CH) | 2005-10-26 | — | — | CN | disclosed |
| CN-1476424-A | Naphthalene derivatives | ��˹��ŵ�� | 2004-02-18 | — | — | CN | disclosed |