Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416577 | 0.91 | PANK3 (0.37) | PANK3HPGDSMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL11426399 | 0.87 | MEN1 (0.38) | PANK3HPGDSMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL11416109 | 0.80 | SMYD3 (0.39) | SMN1; SMN2MAPTMEN1RAB9AKMT2A | |
| SCHEMBL11421496 | 0.78 | NPC1 (0.44) | HPGDSMN1; SMN2MAPTALDH1A1TAS1R3 | |
| SCHEMBL11428620 | 0.77 | NPC1 (0.46) | HPGDSMN1; SMN2MAPTALDH1A1TAS1R3 | |
| SCHEMBL11414719 | 0.77 | NPC1 (0.46) | HPGDSMN1; SMN2MAPTALDH1A1TAS1R3 | |
| SCHEMBL11414466 | 0.76 | HSD17B10 (0.44) | PANK3HPGDSMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL11424750 | 0.73 | HTR1A (0.32) | — | |
| SCHEMBL11417143 | 0.73 | TAS1R3 (0.43) | SMN1; SMN2TAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL11414821 | 0.72 | KMT2A (0.43) | SMN1; SMN2ALDH1A1EPHX2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4194008-A | INSECTICIDE, FUNGICIDE, MITICIDE, PARASITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |