Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | UBE2M | P61081 | 1/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428179 | 0.87 | LMNA (0.68) | SMN1; SMN2LMNAGAAHTTMAPT | |
| SCHEMBL16363122 | 0.87 | KMT2A (0.62) | SMN1; SMN2LMNAGAAHTTMAPT | |
| SCHEMBL11408640 | 0.85 | GAA (0.49) | SMN1; SMN2LMNAGAAHTTMAPT | |
| SCHEMBL11428857 | 0.85 | GAA (0.56) | SMN1; SMN2LMNAGAAHTTMAPT | |
| SCHEMBL11419541 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAMAPTRAB9AKMT2A | |
| SCHEMBL11430785 | 0.84 | KMT2A (0.54) | SMN1; SMN2LMNAGAAHTTMAPT | |
| SCHEMBL11419599 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAGAAHTTMAPT | |
| SCHEMBL11420777 | 0.84 | HTT (0.68) | SMN1; SMN2LMNAHTTMAPTRAB9A | |
| SCHEMBL11432617 | 0.84 | HTT (0.48) | SMN1; SMN2LMNAGAAHTTMAPT | |
| SCHEMBL5471126 | 0.84 | RAB9A (0.65) | SMN1; SMN2HTTMAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183956-A | Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-01-15 | — | — | US | disclosed |