SCHEMBL11429044

SCHEMBL11429044

CC(=O)CCC=CCC(Cl)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
FFAR1 O14842 1/20 0.32
MAPT P10636 1/20 0.32
CYP19A1 P11511 1/20 0.32
RXRA P19793 1/20 0.32
PPARG P37231 1/20 0.32
OXER1 Q8TDS5 1/20 0.32
LMNA P02545 1/20 0.32
SLC15A2 Q16348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11429038 1.00 ALDH1A1 (0.38) ALDH1A1FFAR1MAPTCYP19A1RXRA
SCHEMBL11009268 0.81 ALDH1A1 (0.56) ALDH1A1FFAR1MAPTCYP19A1RXRA
SCHEMBL11009265 0.81 ALDH1A1 (0.56) ALDH1A1FFAR1MAPTCYP19A1RXRA
SCHEMBL1786831 0.80 ALDH1A1 (0.39) ALDH1A1FFAR1MAPTCYP19A1RXRA
SCHEMBL1786833 0.80 ALDH1A1 (0.39) ALDH1A1FFAR1MAPTCYP19A1RXRA
SCHEMBL9498159 0.74 ALDH1A1 (0.47) ALDH1A1FFAR1MAPTCYP19A1PPARG
SCHEMBL9498152 0.74 ALDH1A1 (0.47) ALDH1A1FFAR1MAPTCYP19A1PPARG
SCHEMBL11437994 0.72 KMT2A (0.33) ALDH1A1MAPT
SCHEMBL11437992 0.72 KMT2A (0.33) ALDH1A1MAPT
SCHEMBL672482 0.72 ALDH1A1 (0.45) ALDH1A1FFAR1MAPTCYP19A1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4229470-A Compounds having a trichloromethylic end group having a juvenile hormone action on insects and acaricide activity MONTEDISON S.P.A. (IT) 1980-10-21 US disclosed
US-4140794-A Compounds having a trichloromethylic end group having a juvenile hormone action on insects and acaricide activity MONTEDISON S.P.A. (IT) 1979-02-20 US disclosed
US-4000312-A METHYLENEDIOXY-BENZENE MONTEDISON FIBRE S.P.A. (IT) 1976-12-28 US disclosed