Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 9/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437994 | 1.00 | KMT2A (0.33) | KMT2AGGPS1MEN1CYP3A4ALOX15 | |
| SCHEMBL11431732 | 0.76 | KMT2A (0.43) | KMT2AGGPS1MEN1CYP3A4ALOX15 | |
| SCHEMBL11433041 | 0.76 | KMT2A (0.43) | KMT2AGGPS1MEN1CYP3A4ALOX15 | |
| SCHEMBL11431729 | 0.76 | KMT2A (0.43) | KMT2AGGPS1MEN1CYP3A4ALOX15 | |
| SCHEMBL11548838 | 0.74 | KMT2A (0.30) | KMT2A | |
| SCHEMBL11548840 | 0.74 | KMT2A (0.30) | KMT2A | |
| SCHEMBL11429038 | 0.72 | ALDH1A1 (0.38) | MAPTALDH1A1 | |
| SCHEMBL11429044 | 0.72 | ALDH1A1 (0.38) | MAPTALDH1A1 | |
| SCHEMBL11855524 | 0.70 | KMT2A (0.44) | KMT2AGGPS1MEN1CYP3A4ALOX15 | |
| SCHEMBL11855518 | 0.70 | KMT2A (0.44) | KMT2AGGPS1MEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229470-A | Compounds having a trichloromethylic end group having a juvenile hormone action on insects and acaricide activity | MONTEDISON S.P.A. (IT) | 1980-10-21 | — | — | US | disclosed |
| US-4140794-A | Compounds having a trichloromethylic end group having a juvenile hormone action on insects and acaricide activity | MONTEDISON S.P.A. (IT) | 1979-02-20 | — | — | US | disclosed |