Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10430387 | 0.82 | CYP1A2 (0.46) | CYP1A2SIGMAR1EPHX1HRH3SMN1; SMN2 | |
| SCHEMBL29101110 | 0.82 | CYP1A2 (0.56) | CYP1A2SIGMAR1EPHX1HRH3SMN1; SMN2 | |
| SCHEMBL9267046 | 0.82 | CYP1A2 (0.56) | CYP1A2SIGMAR1EPHX1HRH3SMN1; SMN2 | |
| SCHEMBL14739553 | 0.79 | CYP1A2 (0.52) | CYP1A2SIGMAR1EPHX1HRH3SMN1; SMN2 | |
| SCHEMBL14740174 | 0.75 | SIGMAR1 (0.56) | CYP1A2SIGMAR1EPHX1NAAA | |
| SCHEMBL29101112 | 0.75 | SIGMAR1 (0.56) | CYP1A2SIGMAR1EPHX1NAAA | |
| SCHEMBL1404458 | 0.75 | NFE2L2 (0.42) | CYP1A2SIGMAR1EPHX1HRH3NFE2L2 | |
| SCHEMBL11254475 | 0.74 | CYP1A2 (0.48) | CYP1A2SIGMAR1EPHX1HRH3SMN1; SMN2 | |
| SCHEMBL11022579 | 0.72 | CYP1A2 (0.46) | CYP1A2SIGMAR1EPHX1HRH3SMN1; SMN2 | |
| SCHEMBL6437482 | 0.72 | CYP1A2 (0.64) | CYP1A2SIGMAR1EPHX1HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462168-A2 | MIXED DONOR SYSTEM FOR HIGH MELT FLOW AND HIGH ACTIVITY | BASF Corporation (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017283-A2 | MIXED DONOR SYSTEM FOR HIGH MELT FLOW AND HIGH ACTIVITY | BASF CORPORATION (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20110034651-A1 | MIXED DONOR SYSTEM FOR HIGH MELT FLOW AND HIGH ACTIVITY | BASF CATALYSTS LLC (US) | 2011-02-10 | — | — | US | disclosed |