Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL27715190 | 0.93 | PTGS2 (0.61) | HTR2AMAOAKCNH2ESR1ADRA2A | |
| 4-Phenyl-Butylamine SCHEMBL8353115 | 0.91 | MAOA (0.63) | HTR2AMAOAKCNH2ESR1ADRA2A | |
| 4-Phenyl-Butylamine SCHEMBL8356098 | 0.91 | MAOA (0.63) | HTR2AMAOAKCNH2ESR1ADRA2A | |
| SCHEMBL9158637 | 0.91 | MAOA (0.62) | HTR2AMAOAKCNH2ESR1ADRA2A | |
| Ethylenediamine SCHEMBL28895391 | 0.90 | HTR2A (0.70) | HTR2AMAOAKCNH2ESR1ADRA2A | |
| Propylamine SCHEMBL8977021 | 0.90 | HTR2A (0.70) | HTR2AMAOAKCNH2ESR1ADRA2A | |
| Ethylene Glycol SCHEMBL25429457 | 0.90 | KCNH2 (0.62) | HTR2AKCNH2ESR1ADRA2AADORA3 | |
| Ethylene Glycol SCHEMBL28843886 | 0.90 | KCNH2 (0.62) | HTR2AKCNH2ESR1ADRA2AADORA3 | |
| Ethylene Glycol SCHEMBL27755722 | 0.90 | KCNH2 (0.62) | HTR2AKCNH2ESR1ADRA2AADORA3 | |
| 4-Phenyl-Butylamine SCHEMBL8103485 | 0.89 | MAOA (0.66) | HTR2AMAOAKCNH2ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240076577-A1 | NON-CORROSIVE OVEN DEGREASER CONCENTRATE | ECOLAB USA INC. | 2024-03-07 | — | — | US | disclosed |
| US-11845913-B2 | Non-corrosive oven degreaser concentrate | ECOLAB USA INC. (US) | 2023-12-19 | — | — | US | disclosed |
| US-20180258372-A1 | NON-CORROSIVE OVEN DEGREASER CONCENTRATE | ECOLAB USA INC. | 2018-09-13 | — | — | US | disclosed |
| US-9994798-B2 | Non-corrosive oven degreaser concentrate | ECOLAB USA INC. (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170036189-A1 | Composite Absorbent Particles for Drying an Emulsions | LIANG CHENGUANG (US) | 2017-02-09 | — | — | US | disclosed |
| US-20150203791-A1 | NON-CORROSIVE OVEN DEGREASER CONCENTRATE | ECOLAB USA INC. | 2015-07-23 | — | — | US | disclosed |
| US-9023782-B2 | Non-corrosive oven degreaser concentrate | ECOLAB USA INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20120295829-A1 | NON-CORROSIVE OVEN DEGREASER CONCENTRATE | ECOLAB USA INC. (US) | 2012-11-22 | — | — | US | disclosed |
| US-4186126-A | ALKANOLAMINE SALTS OF ARYL AND/OR ALKYL ARYL SULFONIC ACIDS, SYNTHETIC AND NATURAL POLYMERS | MESSICK JOHN J | 1980-01-29 | — | — | US | disclosed |