Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RORB | Q92753 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428998 | 0.91 | NPSR1 (0.46) | NPSR1MC4RAKR1C3AKR1C2KDM4E | |
| SCHEMBL11441231 | 0.89 | AKR1C3 (0.48) | NPSR1AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL11433951 | 0.87 | BRD9 (0.46) | AKR1C3AKR1C2KDM4EHSD17B10RORB | |
| SCHEMBL11434507 | 0.87 | PTPN5 (0.53) | AKR1C3AKR1C2KDM4ERORBRORC | |
| SCHEMBL11428028 | 0.86 | NR1H4 (0.49) | NPSR1AKR1C3AKR1C2ALDH1A1HPGD | |
| SCHEMBL11428838 | 0.85 | BRD4 (0.49) | NPSR1AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL11434713 | 0.85 | PTPN5 (0.46) | NPSR1AKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL11426704 | 0.84 | BRD9 (0.43) | AKR1C3AKR1C2KDM4EHSD17B10RORB | |
| SCHEMBL11434073 | 0.84 | L3MBTL1 (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| Fluridone SCHEMBL54579 | 0.83 | BRD9 (0.43) | NPSR1AKR1C3AKR1C2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |