Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434447 | 0.92 | GAK (0.48) | L3MBTL1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL11429751 | 0.84 | NPSR1 (0.53) | L3MBTL1MAPTKDM4ETP53HSD17B10 | |
| SCHEMBL11441155 | 0.84 | HSD17B1 (0.49) | BRD4BRD9PTGS2 | |
| SCHEMBL11439506 | 0.81 | PTGS2 (0.44) | MAPTKDM4ETHRBTP53HSD17B10 | |
| SCHEMBL28705161 | 0.77 | MAPT (0.50) | L3MBTL1MAPTKDM4ETHRBNPC1 | |
| SCHEMBL10566304 | 0.74 | ERN1 (0.59) | L3MBTL1MAPTKDM4ETHRBNPC1 | |
| SCHEMBL29385001 | 0.74 | KDM4E (0.55) | MAPTKDM4ETHRBMAPK1PDE4A | |
| SCHEMBL11549399 | 0.72 | BRD4 (0.42) | MAPTKDM4ETHRBNPC1RAB9A | |
| SCHEMBL10565642 | 0.72 | PRKCA (0.44) | L3MBTL1MAPTKDM4ETHRBNPC1 | |
| SCHEMBL8840880 | 0.72 | PDE4A (0.67) | L3MBTL1MAPTKDM4ETHRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |