Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CD40 | P25942 | 1/20 | 0.39 |
| ▸ | CD40LG | P29965 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425199 | 0.92 | KCNMA1 (0.43) | KCNMA1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11437674 | 0.88 | KCNMA1 (0.48) | KCNMA1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11425174 | 0.86 | KCNMA1 (0.51) | KCNMA1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11421989 | 0.85 | KCNMA1 (0.47) | KCNMA1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11431851 | 0.84 | KCNMA1 (0.53) | KCNMA1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11425892 | 0.84 | GRM5 (0.41) | KCNMA1KMT2AMEN1SMN1; SMN2CD40 | |
| SCHEMBL11433116 | 0.84 | GRM5 (0.39) | KCNMA1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11431691 | 0.83 | KCNMA1 (0.54) | KCNMA1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11425195 | 0.82 | MAPT (0.50) | ALDH1A1KMT2AMEN1SMN1; SMN2CD40 | |
| SCHEMBL11423102 | 0.82 | KCNMA1 (0.48) | KCNMA1ALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |