Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433116 | 0.92 | GRM5 (0.39) | GRM5PLAUPHLPP2KCNMA1GLO1 | |
| SCHEMBL11433192 | 0.87 | AURKA (0.43) | GRM5PLAUKCNMA1RAB9APOLB | |
| SCHEMBL11425199 | 0.86 | KCNMA1 (0.43) | GRM5KCNMA1POLBMEN1KMT2A | |
| SCHEMBL11433578 | 0.85 | CD40 (0.42) | PLAURAB9APOLBMEN1KMT2A | |
| SCHEMBL11439444 | 0.84 | TTR (0.43) | GRM5PLAUKCNMA1MEN1KMT2A | |
| SCHEMBL11430359 | 0.84 | KCNMA1 (0.46) | KCNMA1POLBMEN1KMT2ALMNA | |
| SCHEMBL11433621 | 0.83 | SNCA (0.45) | GRM5KCNMA1RAB9AMEN1KMT2A | |
| SCHEMBL11425889 | 0.83 | ENPP2 (0.41) | PHLPP2GLO1RAB9AMEN1KMT2A | |
| SCHEMBL11426487 | 0.82 | AURKA (0.44) | GRM5KCNMA1RAB9AMEN1KMT2A | |
| SCHEMBL11428601 | 0.81 | KDR (0.40) | GRM5KCNMA1RAB9APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |