Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434508 | 0.96 | SMN1; SMN2 (0.60) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11421978 | 0.92 | MEN1 (0.52) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11436835 | 0.90 | MAPT (0.60) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11425117 | 0.88 | MEN1 (0.49) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11433364 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11423367 | 0.84 | HPGD (0.61) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11422986 | 0.84 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11438675 | 0.84 | CASP6 (0.47) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11437659 | 0.84 | MAPT (0.62) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11426110 | 0.83 | MEN1 (0.55) | SMN1; SMN2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |