Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433673 | 0.93 | HPGD (0.52) | HPGDMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11426750 | 0.87 | MEN1 (0.60) | HPGDMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11423176 | 0.85 | MEN1 (0.53) | HPGDMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11437122 | 0.85 | HPGD (0.66) | HPGDMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11430423 | 0.84 | SMN1; SMN2 (0.60) | HPGDMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11442222 | 0.84 | RAB9A (0.59) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11431850 | 0.84 | HPGD (0.62) | HPGDMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11426047 | 0.84 | HPGD (0.62) | HPGDMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11422937 | 0.84 | NPC1 (0.58) | HPGDMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10907766 | 0.83 | ALDH1A1 (0.43) | HPGDMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |