SCHEMBL11430477

SCHEMBL11430477

C=CCS(=O)(=O)OC(N)=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
FGFR4 P22455 1/20 0.32
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10415662 0.80 CA2 (0.30) CA2CA9
SCHEMBL2337505 0.79
SCHEMBL27708588 0.78 CA2 (0.38) CA2CA9
SCHEMBL8586144 0.77 ALDH1A1 (0.31) ALDH1A1
SCHEMBL2178902 0.77 MAPT (0.33)
SCHEMBL11667235 0.77 TSHR (0.37) ALDH1A1TSHR
SCHEMBL9810 0.77 ALDH1A1 (0.32) ALDH1A1
SCHEMBL11304712 0.77
SCHEMBL21823211 0.76 MAPT (0.32)
SCHEMBL1644327 0.76 TSHR (0.35) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4306876-A Aqueous dispersions of primary aromatic amines, their use for the production of water-insoluble azo dyes on the fiber and the use of an anionic surfactant for the manufacture of said dispersions HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-22 US disclosed