Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11442744 | 0.85 | NOX1 (0.42) | L3MBTL1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL11442746 | 0.84 | MEN1 (0.39) | ALOX15CYP19A1CYP11B1CYP11B2TP53 | |
| SCHEMBL11442019 | 0.82 | SMN1; SMN2 (0.41) | TP53L3MBTL1KMT2AKDM4ETSHR | |
| SCHEMBL11430856 | 0.78 | L3MBTL1 (0.42) | TP53L3MBTL1KMT2AKDM4EMAPT | |
| SCHEMBL11427374 | 0.77 | TP53 (0.37) | ALOX15TP53CYP3A4L3MBTL1KMT2A | |
| SCHEMBL11436425 | 0.76 | RAD52 (0.35) | L3MBTL1KMT2ASRD5A1LMNA | |
| SCHEMBL10588135 | 0.75 | ADRA2A (0.41) | TP53CYP3A4L3MBTL1KDM4ETSHR | |
| SCHEMBL11430640 | 0.74 | CYBB (0.42) | ALOX15TP53CYP3A4KMT2ASLC6A2 | |
| SCHEMBL22001571 | 0.70 | NQO1 (0.48) | TP53CYP3A4L3MBTL1KMT2ATSHR | |
| SCHEMBL6980453 | 0.69 | KMT2A (0.49) | TP53CYP3A4L3MBTL1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228284-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4166127-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |